故事发生在 19 世纪末的意大利。杰玛・加尔加尼和世界上数百万年轻人一样，对生活充满热情。她一直渴望加入宗教修会，但命运却为她安排了别样的人生……

The plot centres on the disappearance of the eponymous Gemma after she goes backpacking with a friend in India. When the friend returns from the trip alone, she is haunted by the belief that Gemma's disappearance is her fault, but mystery surrounds what really happened.

The Gemma Factor is a BBC Three sitcom starring Anna Gilthorpe, Claire King and Gwyneth Powell. The series is similar to many current programmes of this sort, by which it is simulcast on BBC Three and BBC HD. The series premiered on Tuesday 9 March 2010, and has six episodes.

Gemma gets a big assignment at work and graduates from therapy, but a blast from the past threatens her security.

When a four year old and other children in same neighborhood develop leukaemia, the parents suspect a nearby factory. Based on real events.

Donizetti's 'Gemma di Vergy' recorded live at the Teatro Donizetti, Bergamo in September 2011.